Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.
Senior / Principal Research Associate, Biologics Discovery
Basel, CH, Tech Park HB-F
Full-time
Permanent employee
About us
Responsibilities
For one of our seed companies we are looking for an experienced Research Associate to support the development and execution of cell-based assays in the context of metabolic diseases.
- Supporting general laboratory duties and maintaining laboratory stocks
- Conducting routine mammalian tissue culture
- Assessing cell surface markers as well as secreted proteins using FACS & ELISA
- Assessing protein expression and mRNA expression by Western Blot and RT-qPCR
- Perform cellular genome engineering using plasmids, lentiviral particles, or CRISPR-Cas9 technologies
- Cellular GPCR activity assessment using reporter gene, cAMP, bArrestin assays, etc.
- Work with primary cell models (e.g., adipocytes, hepatocytes, pancreatic beta cells)
- Developing novel and state of the art cellular assay platforms for metabolic diseases
- Responsible for design, plan and execution of the above-mentioned experiments
- Trouble shooting
- Maintain excellent documentation for lab books and present results in internal meetings
- Supporting colleagues, associates, and scientists with their work
Qualifications
- Apprenticeship with 7+ years experience or B.Sc./M.Sc. degree with equivalent level of experience in Biochemistry, Molecular Biology, Immunology, Bioengineering or related discipline
- 5+ years of experience in assay development
- Experience with cell culture and cell based assays, preferably in metabolic disease models
- Experience with biologicals, preferably mAb or bioconjugates
- Organized with attention to detail and quality driven mindset
- Excellent communication skills, ability to work both independently and as part of a team
- Highly motivated team-player with can-do attitude, flexibility to learn new techniques and passion to work in dynamic and innovative environment
What we currently offer
- People: We are an international and diverse team with talented and passionate people.
- Creativity: We offer an innovative and creative environment.
- Development: We support the individual development of our employees.
- Fun: From time-to-time we organise cool off-site summer and winter team events.
- Offices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
- Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- Flexible Working: We support flexible working as appropriate.
- Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
Please note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement.